Category: BMT/Thalassemia
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Iron Chelation Therapy: Understanding the Treatment for Iron Overload
Iron chelation therapy is a treatment used to remove excess iron from the body. Iron overload can occur as a result of certain medical conditions such as thalassemia and hemochromatosis, or as a complication of blood transfusions. The excess iron can accumulate in various organs of the body and can cause damage to these…
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Beta Thalassemia Major: Understanding the Severe Form of the Blood Disorder
Beta thalassemia major, also known as Cooley’s anemia, is a severe form of the inherited blood disorder thalassemia. It is caused by mutations in the HBB gene, which controls the production of the beta globin subunit of hemoglobin, the protein in red blood cells that carries oxygen to the body’s tissues. The condition leads to…
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Beta Thalassemia Minor: Understanding the Mild Form of the Inherited Blood Disorder
Beta thalassemia is a group of inherited blood disorders that affect the production of the beta globin subunit of hemoglobin, the protein in red blood cells that carries oxygen to the body’s tissues. The condition is characterized by the abnormal formation of hemoglobin, leading to the destruction of red blood cells and a shortage…
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Beta Thalassemia: Understanding the Inherited Blood Disorder
Beta thalassemia is a group of inherited blood disorders that affect the production of beta globin, a component of hemoglobin, the protein in red blood cells that carries oxygen to the body’s tissues. When there is a defect in the HBB gene, which produces the beta globin, the body produces abnormal hemoglobin, leading to…
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Understanding Alpha Thalassemia: Symptoms, Diagnosis, and Treatment
Alpha thalassemia is a genetic blood disorder that affects the production of the alpha globin subunit of hemoglobin, a protein in red blood cells that carries oxygen to the body’s tissues. The condition is caused by mutations in the HBA1 and HBA2 genes and it is passed down from parents to their children through…
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Thalassemia: Understanding the Inherited Blood Disorder
Introduction Thalassemia is a group of inherited blood disorders that affect the production of hemoglobin, the protein in red blood cells that carries oxygen to the body’s tissues. The condition is characterized by the abnormal formation of hemoglobin, leading to the destruction of red blood cells and a shortage of oxygen in the body….
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What disqualifies you from being a bone marrow donor?
There are several factors that can disqualify someone from becoming a bone marrow donor, including certain medical conditions, medications, and lifestyle choices. Some examples include: Active infections or uncontrolled medical conditions, such as cancer, HIV, or heart disease Use of certain medications, such as blood thinners or immunosuppressants Recent tattoos or piercings A history of…
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Dr. Rahul Bhargava Online Appointment
Dr. Rahul Bhargava is a board-certified medical doctor specializing in bone marrow transplantation (BMT). He received his medical degree from a top medical school and completed his residency in internal medicine. He then pursued further training in BMT and completed a fellowship in this field at a renowned medical center. Dr. Bhargava has extensive experience…
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T-Cell Acute Lymphoblastic Leukemia (T-ALL) | BMT
T-cell immunophenotype of acute lymphoblastic leukemia (T-ALL) is an uncommon aggressive leukemia that can present with leukemic and/or lymphomatous manifestations. Molecular studies are enhancing our understanding of the pathogenesis of T-ALL, and the discovery of activating mutations of NOTCH1 and FBXW7 in a majority of patients has been a seminal observation. The use of pediatric intensive combination chemotherapy…